Table 1. Incident ATL cohort Code .... | American Society of Hematology

Table 1.

Incident ATL cohort

Code	Clinical subtype	Stage (lymphoma subtype)	Age at diagnosis, y	Months from HTLV diagnosis to ATL	HTLV-associated disease	Immunomodulatory therapy prior to ATL diagnosis
A1	Acute	n/a	57	32	HAM	None
A2	Acute	n/a	85	118	HAM	Methyl prednisolone
L1	Lymphoma	IVS	54	168	HAM	Cyclosporine
L2	Lymphoma	IVB	51	29	SPA	Methotrexate, anti-TNF, hydroxychloroquine, prednisolone
L3	Lymphoma	IV	53	124	None	None
L4	Lymphoma*	IIA	33	22	SS	None

Code	Clinical subtype	Stage (lymphoma subtype)	Age at diagnosis, y	Months from HTLV diagnosis to ATL	HTLV-associated disease	Immunomodulatory therapy prior to ATL diagnosis
A1	Acute	n/a	57	32	HAM	None
A2	Acute	n/a	85	118	HAM	Methyl prednisolone
L1	Lymphoma	IVS	54	168	HAM	Cyclosporine
L2	Lymphoma	IVB	51	29	SPA	Methotrexate, anti-TNF, hydroxychloroquine, prednisolone
L3	Lymphoma	IV	53	124	None	None
L4	Lymphoma*	IIA	33	22	SS	None

Patients were subtyped according to the Shimoyama classification and Ann Arbor staging systems.

HAM, HTLV-associated myelopathy; n/a, not applicable; SPA, seronegative polyarthritis; SS, Strongyloides stercoralis hyperinfection; TNF, tumor necrosis factor.

This patient also had Epstein-Barr virus–positive cells with Hodgkin disease–like histologic features.³¹

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