Table 2. Discovery candidate selection:... | American Society of Hematology

Table 2.

Discovery candidate selection: comparison of sclerotic chronic GVHD (n = 21) with other conditions (n = 53)

Protein	Mean fold difference in MS		Mean fold difference in Luminex		Consistency	AUC	Candidate
Protein	Male	Female	Male	Female	Consistency	AUC	Candidate
Candidates from MS analysis
C-C motif chemokine ligand 14	0.5	0.6	1.1	1.0	No	0.51	No
DKK3	4.5	2.5	1.3	1.2	Yes	0.64	Yes
IL1RAP	0.6	0.4	0.8	1.0	Yes	0.62	Yes
Interleukin-6 receptor subunit β	3.1	3.9	0.9	0.8	No	0.67	No
Galectin-3-binding protein	0.4	0.4	1.5	1.8	No	0.69	No

Protein	Mean fold difference in MS		Mean fold difference in Luminex		Consistency	AUC	Candidate
Protein	Male	Female	Male	Female	Consistency	AUC	Candidate
Candidates from MS analysis
C-C motif chemokine ligand 14	0.5	0.6	1.1	1.0	No	0.51	No
DKK3	4.5	2.5	1.3	1.2	Yes	0.64	Yes
IL1RAP	0.6	0.4	0.8	1.0	Yes	0.62	Yes
Interleukin-6 receptor subunit β	3.1	3.9	0.9	0.8	No	0.67	No
Galectin-3-binding protein	0.4	0.4	1.5	1.8	No	0.69	No

Boldface type indicates that the protein passed criteria for further evaluation (consistent fold differences between MS and Luminex as well as between males and females, and AUC ≥0.60).

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