Active comorbidity and aGVHD are associated with increased risk for TA-TMA among patients who received haplo-HSCT
Factors . | Number of patients . | TA-TMA (%) . | P . |
---|---|---|---|
Presence of active comorbidity | .05 | ||
Yes | 10 | 4 (60) | |
No | 37 | 4 (10.8) | |
Number of transplant | .05 | ||
First transplant | 42 | 5 (11.9) | |
>1 transplant | 5 | 3 (60) | |
Use of TBI conditioning | .26 | ||
Yes | 6 | 2 (33) | |
No | 41 | 6 (14) | |
CSA/tacrolimus/sirolimus prophylaxis | 1 | ||
Yes | 17 | 3 (17.6) | |
No | 30 | 5 (16) | |
Presence of aGVHD | .06 | ||
Yes | 27 | 7 (25.9) | |
No | 20 | 1 (5) |
Factors . | Number of patients . | TA-TMA (%) . | P . |
---|---|---|---|
Presence of active comorbidity | .05 | ||
Yes | 10 | 4 (60) | |
No | 37 | 4 (10.8) | |
Number of transplant | .05 | ||
First transplant | 42 | 5 (11.9) | |
>1 transplant | 5 | 3 (60) | |
Use of TBI conditioning | .26 | ||
Yes | 6 | 2 (33) | |
No | 41 | 6 (14) | |
CSA/tacrolimus/sirolimus prophylaxis | 1 | ||
Yes | 17 | 3 (17.6) | |
No | 30 | 5 (16) | |
Presence of aGVHD | .06 | ||
Yes | 27 | 7 (25.9) | |
No | 20 | 1 (5) |
Bold numbers indicate a significant change.