Table 7.

Multivariable proportional subdistribution hazards model with competing risks for TRM for allogeneic and autologous HCT recipients with TA-TMA using Cho criteria or Jodele criteria

FactorCho criteriaJodele criteria
Adjusted HR (95% CI)Adjusted PAdjusted HR (95% CI)Adjusted P
TMA 3.0 (1.1-8.2) .003 10.9 (2.6-46.1) .001 
Grade 3/4 aGVHD* 2.9 (1.0-8.0) .04 3.5 (1.3-9.1) .01 
Infection 2.7 (0.9-8.3) .09 2.2 (0.7-7.1) .2 
FactorCho criteriaJodele criteria
Adjusted HR (95% CI)Adjusted PAdjusted HR (95% CI)Adjusted P
TMA 3.0 (1.1-8.2) .003 10.9 (2.6-46.1) .001 
Grade 3/4 aGVHD* 2.9 (1.0-8.0) .04 3.5 (1.3-9.1) .01 
Infection 2.7 (0.9-8.3) .09 2.2 (0.7-7.1) .2 

Bold P values denote association of the factor (TA-TMA, grade 3/4 aGVHD, and infection) with TRM in a multivariable model.

*

Allogeneic recipients only; 7 patients with graft failure were excluded from the analysis.

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