Multivariable proportional subdistribution hazards model with competing risks for TRM for allogeneic and autologous HCT recipients with TA-TMA using Cho criteria or Jodele criteria
Factor . | Cho criteria . | Jodele criteria . | ||
---|---|---|---|---|
Adjusted HR (95% CI) . | Adjusted P . | Adjusted HR (95% CI) . | Adjusted P . | |
TMA | 3.0 (1.1-8.2) | .003 | 10.9 (2.6-46.1) | .001 |
Grade 3/4 aGVHD* | 2.9 (1.0-8.0) | .04 | 3.5 (1.3-9.1) | .01 |
Infection | 2.7 (0.9-8.3) | .09 | 2.2 (0.7-7.1) | .2 |
Factor . | Cho criteria . | Jodele criteria . | ||
---|---|---|---|---|
Adjusted HR (95% CI) . | Adjusted P . | Adjusted HR (95% CI) . | Adjusted P . | |
TMA | 3.0 (1.1-8.2) | .003 | 10.9 (2.6-46.1) | .001 |
Grade 3/4 aGVHD* | 2.9 (1.0-8.0) | .04 | 3.5 (1.3-9.1) | .01 |
Infection | 2.7 (0.9-8.3) | .09 | 2.2 (0.7-7.1) | .2 |
Bold P values denote association of the factor (TA-TMA, grade 3/4 aGVHD, and infection) with TRM in a multivariable model.
Allogeneic recipients only; 7 patients with graft failure were excluded from the analysis.