Best objective tumor response in the total population and by key patient subgroups
| . | Total population, N = 31 . | Response by baseline transplantation status and BV status . | Response by refractory status to first therapy . | |||
|---|---|---|---|---|---|---|
| Received BV after unsuccessful ASCT, n = 16 . | Received BV and ASCT ineligible, n = 8 . | Received BV before unsuccessful ASCT, n = 7 . | Refractory to first therapy, n = 11 . | Not refractory to first therapy, n = 20 . | ||
| ORR (CR + PR), % (95% CI) | 58.1 (39.1-75.5) | 68.8 (41.3-89.0) | 37.5 (8.5-75.5) | 57.1(18.4-90.1) | 54.5 (23.4-83.3) | 60.0 (36.1-80.9) |
| Response, n (%) | ||||||
| CR | 6 (19.4) | 3 (18.8) | 2 (25.0) | 1 (14.3) | 3 (27.3) | 3 (15.0) |
| PR | 12 (38.7) | 8 (50.0) | 1 (12.5) | 3 (42.9) | 3 (27.3) | 9 (45.0) |
| SD | 7 (22.6) | 3 (18.8) | 3 (37.5) | 1 (14.3) | 4 (36.4) | 3 (15.0) |
| PD | 6 (19.4) | 2 (12.5) | 2 (25.0) | 2 (28.6) | 1 (9.1) | 5 (25.0) |
| . | Total population, N = 31 . | Response by baseline transplantation status and BV status . | Response by refractory status to first therapy . | |||
|---|---|---|---|---|---|---|
| Received BV after unsuccessful ASCT, n = 16 . | Received BV and ASCT ineligible, n = 8 . | Received BV before unsuccessful ASCT, n = 7 . | Refractory to first therapy, n = 11 . | Not refractory to first therapy, n = 20 . | ||
| ORR (CR + PR), % (95% CI) | 58.1 (39.1-75.5) | 68.8 (41.3-89.0) | 37.5 (8.5-75.5) | 57.1(18.4-90.1) | 54.5 (23.4-83.3) | 60.0 (36.1-80.9) |
| Response, n (%) | ||||||
| CR | 6 (19.4) | 3 (18.8) | 2 (25.0) | 1 (14.3) | 3 (27.3) | 3 (15.0) |
| PR | 12 (38.7) | 8 (50.0) | 1 (12.5) | 3 (42.9) | 3 (27.3) | 9 (45.0) |
| SD | 7 (22.6) | 3 (18.8) | 3 (37.5) | 1 (14.3) | 4 (36.4) | 3 (15.0) |
| PD | 6 (19.4) | 2 (12.5) | 2 (25.0) | 2 (28.6) | 1 (9.1) | 5 (25.0) |