Opioid-related adverse effects
| . | Complication . |
|---|---|
| Central nervous system | Sedation |
| Addiction | |
| Tolerance | |
| Witddrawal | |
| Sleep disturbances (reduced total sleep time, sleep efficiency, delta sleep, rapid eye movement sleep) | |
| Reduced psychomotor performance | |
| Myoclonus | |
| Seizures | |
| Delirium | |
| Hallucinations | |
| Head | Dry mouth |
| Miosis | |
| Pulmonary | Antitussive |
| Bronchospasm | |
| Cardiac | QT prolongation |
| Bradycardia | |
| Hypotension | |
| Gastrointestinal | Constipation |
| Nausea | |
| Cholestasis | |
| Hormonal | Reduced libido |
| Erectile dysfunction | |
| Reduced energy | |
| Osteoporosis | |
| Amenorrhea/hypomenorrhea | |
| Urinary | Urinary retention |
| Peripheral | Sweating |
| Pruritus | |
| Sensory | Hyperalgesia |
| Allodynia | |
| Immunologic | Immunosuppression |
| Protumerogenic cytokine stimulation |
| . | Complication . |
|---|---|
| Central nervous system | Sedation |
| Addiction | |
| Tolerance | |
| Witddrawal | |
| Sleep disturbances (reduced total sleep time, sleep efficiency, delta sleep, rapid eye movement sleep) | |
| Reduced psychomotor performance | |
| Myoclonus | |
| Seizures | |
| Delirium | |
| Hallucinations | |
| Head | Dry mouth |
| Miosis | |
| Pulmonary | Antitussive |
| Bronchospasm | |
| Cardiac | QT prolongation |
| Bradycardia | |
| Hypotension | |
| Gastrointestinal | Constipation |
| Nausea | |
| Cholestasis | |
| Hormonal | Reduced libido |
| Erectile dysfunction | |
| Reduced energy | |
| Osteoporosis | |
| Amenorrhea/hypomenorrhea | |
| Urinary | Urinary retention |
| Peripheral | Sweating |
| Pruritus | |
| Sensory | Hyperalgesia |
| Allodynia | |
| Immunologic | Immunosuppression |
| Protumerogenic cytokine stimulation |