Viability was determined after 24 hours of treatment with increasing concentrations of venetoclax and A1155463 (0.001-10 μM) or A1210477 (5 μM). Cell death was assessed by flow cytometry after Annexin V staining. LD50 values for venetoclax (Ven) and A1155463 were calculated from 3 independent experiments. Apoptosis % induced by 5 μM A1210477 is indicated. Red, high (LD50 <300 nM for Ven and A115543, ≥65% apoptosis for 5 μM A1210477). Orange, intermediate (LD50 300 ≤1000 nM for Ven and A115543, 33-65% apoptosis for 5 μM A1210477). Green, not dependent (LD50 >1000 nM for Ven and A115543, <33% apoptosis for 5 μM A1210477).