Clinical phenotypes
| Clinical phenotype . | Frequency . | ||
|---|---|---|---|
| Type . | Definition . | n . | % . |
| 1 | Hemolytic anemia with circulatory symptoms grade 1 or absent | 146 | 69.5 |
| 2 | Hemolytic anemia with circulatory symptoms grade 2-3 | 44 | 21.0 |
| 3 | Circulatory symptoms with compensated hemolysis | 20 | 9.5 |
| All patients with available data | 210 | 100.0 | |
| Clinical phenotype . | Frequency . | ||
|---|---|---|---|
| Type . | Definition . | n . | % . |
| 1 | Hemolytic anemia with circulatory symptoms grade 1 or absent | 146 | 69.5 |
| 2 | Hemolytic anemia with circulatory symptoms grade 2-3 | 44 | 21.0 |
| 3 | Circulatory symptoms with compensated hemolysis | 20 | 9.5 |
| All patients with available data | 210 | 100.0 | |
Circulatory symptoms grade 1, acrocyanosis only; grade 2, Raynaud-like symptoms interfering with daily living; grade 3, gangrene or ulcerations.