Table 2. Phenotype of fungus-specific T... | American Society of Hematology

Table 2.

Phenotype of fungus-specific T cells expanded using individual fungal lysates

	NK	NKT	T cells	CD3⁺CD8⁺	CD3⁺CD4⁺	CD4⁺T_em	CD4⁺T_cm	CD4⁺T_eff	CD4⁺ Naive	CD4⁺ PD-1	CD4⁺ CTLA4	CD4⁺ TIM-3
AF	0.5 ± 0.5	1.4 ± 1	97.2 ± 1.4	5.9 ± 5.9	88.4 ± 10.9	53.0 ± 21.0	30.9 ± 10.7	6.6 ± 4.5	9.5 ± 9	39.3 ± 17.3	3.0 ± 4	22.2 ± 16.1
CK	0.3 ± 0.2	1.3 ± 0.7	97.4 ± 1.5	2.5 ± 1.5	94.0 ± 0.2	70.4 ± 18.9	27.4 ± 17.8	1.1 ± 0.7	1.0 ± 0.8	28.3 ± 18.2	3.8 ± 2.8	41.4 ± 28.4
AT	0.3 ± 0.2	0.9 ± 0.7	97.9 ± 1.6	3.2 ± 2.4	92.3 ± 3.6	65.1 ± 4.9	31.7 ± 5.6	1.6 ± 0.8	1.6 ± 0.5	30.3 ± 17.3	3.7 ± 3.3	30.2 ± 15.4
RO	4.7 ± 3.8	10.6 ± 8.6	82.7 ± 11.2	21.9 ± 20.2	64.7 ± 20.1	42.6 ± 11.4	28.8 ± 13.8	9.8 ± 3.4	18.8 ± 20.6	51.6 ± 13.7	4.5 ± 2.7	44.7 ± 19.6

	NK	NKT	T cells	CD3⁺CD8⁺	CD3⁺CD4⁺	CD4⁺T_em	CD4⁺T_cm	CD4⁺T_eff	CD4⁺ Naive	CD4⁺ PD-1	CD4⁺ CTLA4	CD4⁺ TIM-3
AF	0.5 ± 0.5	1.4 ± 1	97.2 ± 1.4	5.9 ± 5.9	88.4 ± 10.9	53.0 ± 21.0	30.9 ± 10.7	6.6 ± 4.5	9.5 ± 9	39.3 ± 17.3	3.0 ± 4	22.2 ± 16.1
CK	0.3 ± 0.2	1.3 ± 0.7	97.4 ± 1.5	2.5 ± 1.5	94.0 ± 0.2	70.4 ± 18.9	27.4 ± 17.8	1.1 ± 0.7	1.0 ± 0.8	28.3 ± 18.2	3.8 ± 2.8	41.4 ± 28.4
AT	0.3 ± 0.2	0.9 ± 0.7	97.9 ± 1.6	3.2 ± 2.4	92.3 ± 3.6	65.1 ± 4.9	31.7 ± 5.6	1.6 ± 0.8	1.6 ± 0.5	30.3 ± 17.3	3.7 ± 3.3	30.2 ± 15.4
RO	4.7 ± 3.8	10.6 ± 8.6	82.7 ± 11.2	21.9 ± 20.2	64.7 ± 20.1	42.6 ± 11.4	28.8 ± 13.8	9.8 ± 3.4	18.8 ± 20.6	51.6 ± 13.7	4.5 ± 2.7	44.7 ± 19.6

Results are mean ± SD. In all cultures CD19 and CD14 constituted <0.5%.

Naive, naive T cells (CD62L⁺CD45RA⁺); NK, natural killer; NKT, natural killer T cell; T_cm, central memory T cells (CD62L⁺CD45RA⁻); T_eff, effector T cells (CD62L⁻CD45RA⁺); T_em, effector memory T cells (CD62L⁻CD45RA⁻).

View Large

This Feature Is Available To Subscribers Only