Complications posttransplantation (N = 44)
Complication . | Value . |
---|---|
Engraftment syndrome, n (%) | 16 (36) |
Acute GVHD, n (% of GVHD) | 21 (48) |
Grade I | 9 (43) |
Skin only | 9 (43) |
Grade II | 7 (33) |
Skin only | 6 (29) |
Skin + gastrointestinal | 1 (5) |
Grade III | 5 (24) |
Skin + gastrointestinal | 2 (10) |
Gastrointestinal only | 3 (14) |
Grade IV | 0 (0) |
GVHD grade I-IV onset, median (range), d | 47 (13-145) |
GVHD grade II-IV onset, median (range), d | 39.5 (14-145) |
Whole-blood chimerism (donor percentage) at 1 y (n = 37), n (%) | |
>95% | 28 (76) |
90-95% | 2 (5) |
75-89% | 5 (14) |
50-74% | 1 (3) |
25-49% | 1 (3) |
<25% | 0 (0) |
T-cell chimerism (donor percentage) at 1 y (n = 35), n (%) | |
>95% | 22 (63) |
90%-95% | 5 (14) |
75%-89% | 4 (11) |
50%-74% | 3 (9) |
25%-49% | 1 (3) |
<25% | 0 (0) |
Opportunistic infections at 1 y, n (% of infections) | 27 (61) |
Adenovirus | 11 (41) |
EBV | 10 (37) |
HHV-6 | 9 (33) |
CMV | 6 (22) |
Mycobacteria | 1 (4) |
Fungal | 1 (4) |
Complication . | Value . |
---|---|
Engraftment syndrome, n (%) | 16 (36) |
Acute GVHD, n (% of GVHD) | 21 (48) |
Grade I | 9 (43) |
Skin only | 9 (43) |
Grade II | 7 (33) |
Skin only | 6 (29) |
Skin + gastrointestinal | 1 (5) |
Grade III | 5 (24) |
Skin + gastrointestinal | 2 (10) |
Gastrointestinal only | 3 (14) |
Grade IV | 0 (0) |
GVHD grade I-IV onset, median (range), d | 47 (13-145) |
GVHD grade II-IV onset, median (range), d | 39.5 (14-145) |
Whole-blood chimerism (donor percentage) at 1 y (n = 37), n (%) | |
>95% | 28 (76) |
90-95% | 2 (5) |
75-89% | 5 (14) |
50-74% | 1 (3) |
25-49% | 1 (3) |
<25% | 0 (0) |
T-cell chimerism (donor percentage) at 1 y (n = 35), n (%) | |
>95% | 22 (63) |
90%-95% | 5 (14) |
75%-89% | 4 (11) |
50%-74% | 3 (9) |
25%-49% | 1 (3) |
<25% | 0 (0) |
Opportunistic infections at 1 y, n (% of infections) | 27 (61) |
Adenovirus | 11 (41) |
EBV | 10 (37) |
HHV-6 | 9 (33) |
CMV | 6 (22) |
Mycobacteria | 1 (4) |
Fungal | 1 (4) |
EBV, Epstein-Barr virus; HHV, human herpesvirus 6.