Clinical outcomes
Clinical status . | CP (n = 20) . | Matched controls (n = 20) . | ||||
---|---|---|---|---|---|---|
Baseline (d 0) . | Status at 7-d follow-up . | Status at 14-d follow-up . | Baseline* . | Status at 7-d follow-up . | Status at 14-d follow-up . | |
WHO ordinal scale score | ||||||
Median (IQR) | 5 (4.0-6.3) | 4.5 (4.0-6.0) | 3.5 (0-6) | 5 (4-7) | 4.5 (0.8-7.3) | 3 (0-8) |
Mean (SD) | 5.2 (1.3) | 5.07 (1.4) | 3.1 (3.1) | 5.4 (1.4) | 4.2 (3.2) | 3.45 (3.6) |
VTE | 4 (20) | 4 (20) | 4 (20) | 4 (20) | 4 (20) | 4 (20) |
ICU | ||||||
MV | 6 (30) | 6 (30) | 4 (20) | 6 (30) | 5 (25) | 1 (5) |
Duration of MV (IQR), d | 14.5 (6-17.8) | 11.5 (7.5-9.8) | 16.5 (12.8-20) | 3 (2.3-3.8) | 9 (7-0) | 11 (8.5-13.5) |
Extubated survivors | — | 1 (5) | 2 (10) | — | 0 (0) | 3 (15) |
Adverse event after CP | 0 (0) | 0 (0) | 0 (0) | — | — | — |
Hospital stay, d | ||||||
LOS prior to CP, median (range) | 2 (1-21) | — | — | — | — | — |
LOS prior to CP, median (IQR) | 2 (1-4.3) | — | — | — | — | — |
Total LOS, median (IQR) | — | 9 (8-11.3) | 15 (10-16.5) | — | 8 (7-9.5) | 9 (7-13.5) |
LOS of nonsurvivors, median (IQR) | — | 19.5 (15.8-23.3) | 19.5 (15.8-23.3) | — | 8 (7-9) | 8.5 (7.3-10.5) |
LOS of survivors, median (IQR) | — | 9 (8-10) | 15 (10-16) | — | 8 (7-9.5) | 10 (7.3-15) |
Discharged | — | 5 (25) | 9 (45) | — | 7 (35) | 9 (45) |
Deaths | — | 2 (10) | 2 (10) | — | 5 (25) | 6 (30) |
CP given prior to 7 d of hospitalization | — | 0 (0) | 0 (0) | — | 4 (20) | 5 (25) |
CP given after 7 d of hospitalization | — | 2 (10) | 2 (10) | — | 1 (5) | 1 (5) |
Clinical status . | CP (n = 20) . | Matched controls (n = 20) . | ||||
---|---|---|---|---|---|---|
Baseline (d 0) . | Status at 7-d follow-up . | Status at 14-d follow-up . | Baseline* . | Status at 7-d follow-up . | Status at 14-d follow-up . | |
WHO ordinal scale score | ||||||
Median (IQR) | 5 (4.0-6.3) | 4.5 (4.0-6.0) | 3.5 (0-6) | 5 (4-7) | 4.5 (0.8-7.3) | 3 (0-8) |
Mean (SD) | 5.2 (1.3) | 5.07 (1.4) | 3.1 (3.1) | 5.4 (1.4) | 4.2 (3.2) | 3.45 (3.6) |
VTE | 4 (20) | 4 (20) | 4 (20) | 4 (20) | 4 (20) | 4 (20) |
ICU | ||||||
MV | 6 (30) | 6 (30) | 4 (20) | 6 (30) | 5 (25) | 1 (5) |
Duration of MV (IQR), d | 14.5 (6-17.8) | 11.5 (7.5-9.8) | 16.5 (12.8-20) | 3 (2.3-3.8) | 9 (7-0) | 11 (8.5-13.5) |
Extubated survivors | — | 1 (5) | 2 (10) | — | 0 (0) | 3 (15) |
Adverse event after CP | 0 (0) | 0 (0) | 0 (0) | — | — | — |
Hospital stay, d | ||||||
LOS prior to CP, median (range) | 2 (1-21) | — | — | — | — | — |
LOS prior to CP, median (IQR) | 2 (1-4.3) | — | — | — | — | — |
Total LOS, median (IQR) | — | 9 (8-11.3) | 15 (10-16.5) | — | 8 (7-9.5) | 9 (7-13.5) |
LOS of nonsurvivors, median (IQR) | — | 19.5 (15.8-23.3) | 19.5 (15.8-23.3) | — | 8 (7-9) | 8.5 (7.3-10.5) |
LOS of survivors, median (IQR) | — | 9 (8-10) | 15 (10-16) | — | 8 (7-9.5) | 10 (7.3-15) |
Discharged | — | 5 (25) | 9 (45) | — | 7 (35) | 9 (45) |
Deaths | — | 2 (10) | 2 (10) | — | 5 (25) | 6 (30) |
CP given prior to 7 d of hospitalization | — | 0 (0) | 0 (0) | — | 4 (20) | 5 (25) |
CP given after 7 d of hospitalization | — | 2 (10) | 2 (10) | — | 1 (5) | 1 (5) |
Unless otherwise noted, all data are n (%).
LOS, length of stay; —, not applicable.
Baseline day 0 for matched controls corresponds to equivalent hospital day as CP transfusion.