Table 2. Mutations and VAF found in the... | American Society of Hematology

Table 2.

Mutations and VAF found in the BM and PB samples from healthy volunteers with CH

UPN	Age, y	Gene	Mutation	VAF BM, %	VAF PB, %
#33	28	TET2	p.Lys1877Glu	1.1	0.6
#36	47	JAK2	p.Val617Phe	3.1	1.3
#84	52	DNMT3A	p.Arg771*	1.2	1.8
#05	53	TET2	p.Ala295fs1	1	0.5
		DNMT3A	p.? Splice	2.1	1.8
#68	54	DNMT3A	p.Ile310_Val328del	5.6	5.9
#101	54	TET2	p.His1904Arg	4.7	4.5
#13	59	DNMT3A	p.? Splice	15	13
		TET2	p.Gly1154Asp	14	11.2
#43	61	JAK2	p.Val617Phe	3.2	4.2
#99	61	TET2	p.Cys484Leufs*2	2.2	2
#49	63	DNMT3A	p.Tyr735Ser	3.4	1.4
#30	63	DNMT3A	p.Arg736Cys	3.2	1.5
#44	63	DNMT3A	p.Ile310Ser	5.2	4.2
#45	66	SRSF2	p.Tyr44His	1.4	1.7
#47	66	RAD21	p.Leu393Pro	2.7	ND
#72	67	TET2	p.Cys1289Tyr	1	0.5
#38	69	ASXL1	p.Cys1527*	49.4	50.8
		TET2	p.Leu446*	4.9	4.2
#53	70	DNMT3A	p.Leu347Gln	4.3	ND
		DNMT3A	p.Ser714Cys	4.2	ND
		DNMT3A	p.Arg882His	1.8	ND
#78	71	ASXL1	p.Gly649*	9	11
#29	72	DNMT3A	p.Glu578Gly	5.1	4.5
		DNMT3A	p.R882H	1.6	1.6

UPN	Age, y	Gene	Mutation	VAF BM, %	VAF PB, %
#33	28	TET2	p.Lys1877Glu	1.1	0.6
#36	47	JAK2	p.Val617Phe	3.1	1.3
#84	52	DNMT3A	p.Arg771*	1.2	1.8
#05	53	TET2	p.Ala295fs1	1	0.5
		DNMT3A	p.? Splice	2.1	1.8
#68	54	DNMT3A	p.Ile310_Val328del	5.6	5.9
#101	54	TET2	p.His1904Arg	4.7	4.5
#13	59	DNMT3A	p.? Splice	15	13
		TET2	p.Gly1154Asp	14	11.2
#43	61	JAK2	p.Val617Phe	3.2	4.2
#99	61	TET2	p.Cys484Leufs*2	2.2	2
#49	63	DNMT3A	p.Tyr735Ser	3.4	1.4
#30	63	DNMT3A	p.Arg736Cys	3.2	1.5
#44	63	DNMT3A	p.Ile310Ser	5.2	4.2
#45	66	SRSF2	p.Tyr44His	1.4	1.7
#47	66	RAD21	p.Leu393Pro	2.7	ND
#72	67	TET2	p.Cys1289Tyr	1	0.5
#38	69	ASXL1	p.Cys1527*	49.4	50.8
		TET2	p.Leu446*	4.9	4.2
#53	70	DNMT3A	p.Leu347Gln	4.3	ND
		DNMT3A	p.Ser714Cys	4.2	ND
		DNMT3A	p.Arg882His	1.8	ND
#78	71	ASXL1	p.Gly649*	9	11
#29	72	DNMT3A	p.Glu578Gly	5.1	4.5
		DNMT3A	p.R882H	1.6	1.6

ND, no data; UPN, uniform patient number.