Patient, donor, and allograft characteristics (N = 96)
| Characteristic . | Value . |
|---|---|
| Age at BMT, median (range), y | 42 (1-65) |
| Patient sex, male, n (%) | 56 (58) |
| Disease, n (%) | |
| AML | 41 (43) |
| CR1 | |
| MRDneg | 19 |
| MRDpos | 9 |
| CR ≥2 | |
| MRDneg | 10 |
| MRDpos | 3 |
| ALL | 20 (21) |
| CR1 | |
| MRDneg | 9 |
| MRDpos | 2 |
| CR ≥2 | |
| MRDneg | 5 |
| MRDpos | 4 |
| Mixed lineage leukemia | 5 (5) |
| MDS | 11 (11.5) |
| Active | 8 |
| Lymphoma | 11 (11.5) |
| CR | 6 |
| Partial remission | 5 |
| Chronic myeloid leukemia | 4 (4) |
| Other | 4 (4) |
| DRI, n (%) | |
| Low | 6 (6) |
| Intermediate | 61 (64) |
| High | 29 (30) |
| Conditioning, n (%) | |
| Bu/Cy | 73 (76) |
| Cy/TBI | 23 (24) |
| Donor age, median (range), y | 37 (11-77) |
| Donor sex, male, n (%) | 44 (46) |
| Sex mismatch, n (%) | |
| Female donor to male recipient | 30 (31) |
| Male donor to female recipient | 18 (19) |
| None | 48 (50) |
| Graft cell counts | |
| Nucleated cells/kg infused × 108 | 4.8 (2.4-11.2) |
| CD34+/kg infused × 106 | 4.8 (0.3-35) |
| CD3+/kg infused × 107 | 4.6 (3.7-11.6) |
| CMV at risk, n (%) | 53 (55) |
| Median no. of HLA allele mismatches | 4/10 |
| ABO incompatibility, n (%) | |
| Major | 8 (8) |
| Minor | 15 (16) |
| None | 73 (76) |
| Characteristic . | Value . |
|---|---|
| Age at BMT, median (range), y | 42 (1-65) |
| Patient sex, male, n (%) | 56 (58) |
| Disease, n (%) | |
| AML | 41 (43) |
| CR1 | |
| MRDneg | 19 |
| MRDpos | 9 |
| CR ≥2 | |
| MRDneg | 10 |
| MRDpos | 3 |
| ALL | 20 (21) |
| CR1 | |
| MRDneg | 9 |
| MRDpos | 2 |
| CR ≥2 | |
| MRDneg | 5 |
| MRDpos | 4 |
| Mixed lineage leukemia | 5 (5) |
| MDS | 11 (11.5) |
| Active | 8 |
| Lymphoma | 11 (11.5) |
| CR | 6 |
| Partial remission | 5 |
| Chronic myeloid leukemia | 4 (4) |
| Other | 4 (4) |
| DRI, n (%) | |
| Low | 6 (6) |
| Intermediate | 61 (64) |
| High | 29 (30) |
| Conditioning, n (%) | |
| Bu/Cy | 73 (76) |
| Cy/TBI | 23 (24) |
| Donor age, median (range), y | 37 (11-77) |
| Donor sex, male, n (%) | 44 (46) |
| Sex mismatch, n (%) | |
| Female donor to male recipient | 30 (31) |
| Male donor to female recipient | 18 (19) |
| None | 48 (50) |
| Graft cell counts | |
| Nucleated cells/kg infused × 108 | 4.8 (2.4-11.2) |
| CD34+/kg infused × 106 | 4.8 (0.3-35) |
| CD3+/kg infused × 107 | 4.6 (3.7-11.6) |
| CMV at risk, n (%) | 53 (55) |
| Median no. of HLA allele mismatches | 4/10 |
| ABO incompatibility, n (%) | |
| Major | 8 (8) |
| Minor | 15 (16) |
| None | 73 (76) |