Table 1. Patient demographic... | American Society of Hematology

Table 1.

Patient demographic characteristics for the 3 clinical trials used to develop pharmacometric models for FX and FII

Characteristic	Sarode et al¹² (n = 98)	Goldstein et al¹³ (n = 84)*	Kushimoto et al¹⁴ (n = 11)†
Sex, male, n (%)	52 (53)	48 (57)	7 (64)
Mean age (SD), y	70.3 (13.6)	69.5 (13.4)	79.5 (12.7)
Mean weight (SD), kg	80.3 (26.0)	80.7 (20.3)	58.0 (11.8)
Mean baseline INR (SD)	5.03 (3.21)	3.54 (2.24)	4.48 (2.74)

Characteristic	Sarode et al¹² (n = 98)	Goldstein et al¹³ (n = 84)*	Kushimoto et al¹⁴ (n = 11)†
Sex, male, n (%)	52 (53)	48 (57)	7 (64)
Mean age (SD), y	70.3 (13.6)	69.5 (13.4)	79.5 (12.7)
Mean weight (SD), kg	80.3 (26.0)	80.7 (20.3)	58.0 (11.8)
Mean baseline INR (SD)	5.03 (3.21)	3.54 (2.24)	4.48 (2.74)

For FX, mean number of samples per patient was 5.64; for FII, mean number of samples per patient was 5.59.

SD, standard deviation.

FX analysis included 84 patients; FII analysis included 83 patients.

Japanese patients.