Demographic and clinical characteristics of patients with and without major bleeding events
| Characteristic . | Bleeding event (n = 89) . | No bleeding event (n = 167) . | P . |
|---|---|---|---|
| Age, median (range), y | 65 (19-86) | 67 (24-92) | .373 |
| Race, n (%) | .140 | ||
| White | 72 (80.9) | 113 (67.8) | |
| Hispanic | 1 (1.1) | 2 (1.2) | |
| African American | 14 (15.7) | 48 (28.7) | |
| Asian | 2 (2.3) | 4 (2.4) | |
| ICU, n (%) | 66 (74.2) | 68 (40.7) | <.001 |
| Primary service, n (%) | .022 | ||
| Surgical | 56 (62.9) | 80 (47.9) | |
| Medical | 33 (37.1) | 87 (52.1) | |
| Sepsis, n (%)* | 37 (41.6) | 33 (19.8) | <.001 |
| Platelet count on day of blood sample collection, median (range), ×109/L† | 54.5 (8-200) | 79 (13-422) | .0004 |
| Serotonin release assay, n (%) | .863 | ||
| Positive | 10 (11.2) | 15 (8.9) | |
| Indeterminate | 1 (1.1) | 1 (0.6) | |
| Negative | 77 (86.5) | 150 (89.8) | |
| Missing | 1 (1.1) | 1 (0.6) | |
| PF4/H ELISA OD, n (%) | .749 | ||
| <0.4 | 63 (70.8) | 117 (70.1) | |
| 0.4-1.0 | 7 (7.9) | 16 (9.6) | |
| 1.0-2.0 | 7 (7.9) | 17 (10.2) | |
| >2.0 | 12 (13.5) | 16 (9.6) | |
| Missing | 0 (0) | 2 (1.2) | |
| HIT status, n (%) | .509 | ||
| Positive | 15 (16.9) | 23 (13.8) | |
| Negative | 74 (83.5) | 144 (86.2) |
| Characteristic . | Bleeding event (n = 89) . | No bleeding event (n = 167) . | P . |
|---|---|---|---|
| Age, median (range), y | 65 (19-86) | 67 (24-92) | .373 |
| Race, n (%) | .140 | ||
| White | 72 (80.9) | 113 (67.8) | |
| Hispanic | 1 (1.1) | 2 (1.2) | |
| African American | 14 (15.7) | 48 (28.7) | |
| Asian | 2 (2.3) | 4 (2.4) | |
| ICU, n (%) | 66 (74.2) | 68 (40.7) | <.001 |
| Primary service, n (%) | .022 | ||
| Surgical | 56 (62.9) | 80 (47.9) | |
| Medical | 33 (37.1) | 87 (52.1) | |
| Sepsis, n (%)* | 37 (41.6) | 33 (19.8) | <.001 |
| Platelet count on day of blood sample collection, median (range), ×109/L† | 54.5 (8-200) | 79 (13-422) | .0004 |
| Serotonin release assay, n (%) | .863 | ||
| Positive | 10 (11.2) | 15 (8.9) | |
| Indeterminate | 1 (1.1) | 1 (0.6) | |
| Negative | 77 (86.5) | 150 (89.8) | |
| Missing | 1 (1.1) | 1 (0.6) | |
| PF4/H ELISA OD, n (%) | .749 | ||
| <0.4 | 63 (70.8) | 117 (70.1) | |
| 0.4-1.0 | 7 (7.9) | 16 (9.6) | |
| 1.0-2.0 | 7 (7.9) | 17 (10.2) | |
| >2.0 | 12 (13.5) | 16 (9.6) | |
| Missing | 0 (0) | 2 (1.2) | |
| HIT status, n (%) | .509 | ||
| Positive | 15 (16.9) | 23 (13.8) | |
| Negative | 74 (83.5) | 144 (86.2) |
ELISA, enzyme-linked immunosorbent assay; OP, optical density; PF4/H, platelet factor 4/heparin.
International Classification of Diseases, Ninth Revision, code for sepsis during admission that sGPVI was drawn.
Platelet count on day of blood sample collection (first count of day). Nine patients were missing a platelet count on day of blood sample collection.