Table 2.

Univariate and multivariable logistic regression model for predictors of bleeding

VariableUnivariable logistic regressionMultivariable logistic regression
OR (95% CI)POR (95% CI)P
sGPVI     
 <43 ng/mL 1 (Ref) — 1 (Ref) — 
  ≥43 ng/mL 4.59 (2.65-7.96) <.001 2.81 (1.51-5.23) .001 
ICU status*     
 No 1(Ref) — 1 (Ref) — 
 Yes 4.18 (2.37-7.36) <.001 2.76 (1.46-5.21) .002 
Sepsis     
 No 1 (Ref) — 1 (Ref) — 
 Yes 2.89 (1.64-5.10) <.001 2.27 (1.13-4.56) .021 
Cardiopulmonary bypass surgery     
 No 1 (ref) — 1 (Ref) — 
 Yes 1.79 (1.04- 3.07) .036 1.50 (0.76-2.93) .238 
Platelet count, ×109/L     
  ≥151 1 (Ref) — 1 (Ref) — 
 150-100 1.44 (0.44-4.67) .542 0.89 (0.25- 3.22) .858 
 50-100 1.26 (0.42-3.74) .680 0.86 (0.26- 2.81) .801 
  ≤49 3.58 (1.20-10.66) .222 1.72 (0.52- 5.66) .376 
VariableUnivariable logistic regressionMultivariable logistic regression
OR (95% CI)POR (95% CI)P
sGPVI     
 <43 ng/mL 1 (Ref) — 1 (Ref) — 
  ≥43 ng/mL 4.59 (2.65-7.96) <.001 2.81 (1.51-5.23) .001 
ICU status*     
 No 1(Ref) — 1 (Ref) — 
 Yes 4.18 (2.37-7.36) <.001 2.76 (1.46-5.21) .002 
Sepsis     
 No 1 (Ref) — 1 (Ref) — 
 Yes 2.89 (1.64-5.10) <.001 2.27 (1.13-4.56) .021 
Cardiopulmonary bypass surgery     
 No 1 (ref) — 1 (Ref) — 
 Yes 1.79 (1.04- 3.07) .036 1.50 (0.76-2.93) .238 
Platelet count, ×109/L     
  ≥151 1 (Ref) — 1 (Ref) — 
 150-100 1.44 (0.44-4.67) .542 0.89 (0.25- 3.22) .858 
 50-100 1.26 (0.42-3.74) .680 0.86 (0.26- 2.81) .801 
  ≤49 3.58 (1.20-10.66) .222 1.72 (0.52- 5.66) .376 

Ref, reference.

*

Hospitalized in a medical or surgical critical care unit at time of enrollment in study.

International Classification of Diseases, Ninth Revision, code for sepsis during hospitalization sGPVI level as drawn.

Platelet count on day of sGPVI blood draw.

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