Novel RH gene SNPs identified in 884 patients with SCD
| Gene . | Exon . | Coding position . | Class . | Amino acid position . | Samples, n . |
|---|---|---|---|---|---|
| RHD | 1 | 105 C>T | Silent | Asp35Asp | 1 |
| 3 | 364 T>A* | Missense | Ser122Thr | 1 | |
| 3 | 473 G>A* | Missense | Ser158Asn | 1 | |
| 4 | 541 C>T | Silent | Leu181Leu | 6 | |
| RHCE | 2 | 285 C>T | Silent | Asp95Asp | 1 |
| 2 | 321 C>T | Silent | Val107Val | 4 | |
| 3 | 456 C>T | Silent | Thr152Thr | 2 | |
| 5 | 681 G>C | Silent | Leu227Leu | 1 |
| Gene . | Exon . | Coding position . | Class . | Amino acid position . | Samples, n . |
|---|---|---|---|---|---|
| RHD | 1 | 105 C>T | Silent | Asp35Asp | 1 |
| 3 | 364 T>A* | Missense | Ser122Thr | 1 | |
| 3 | 473 G>A* | Missense | Ser158Asn | 1 | |
| 4 | 541 C>T | Silent | Leu181Leu | 6 | |
| RHCE | 2 | 285 C>T | Silent | Asp95Asp | 1 |
| 2 | 321 C>T | Silent | Val107Val | 4 | |
| 3 | 456 C>T | Silent | Thr152Thr | 2 | |
| 5 | 681 G>C | Silent | Leu227Leu | 1 |
RHD pseudogene (RHD*Ψ) associated.