Table 4.

Classification of the response based on depth of response

MRD response criteriaAbbreviationLevel of reduction
MRD grade 3 MRD3 Nonclonal plasma cells or clonotypes between 10−3 and 10−4 
MRD grade 4 MRD4 Nonclonal plasma cells or clonotypes between 10−4 and 10−5 
MRD grade 5 MRD5 Nonclonal plasma cells or clonotypes between 10−5 and 10−6 
MRD grade 6 MRD6 Nonclonal plasma cells or clonotypes <10−6 
MRD response criteriaAbbreviationLevel of reduction
MRD grade 3 MRD3 Nonclonal plasma cells or clonotypes between 10−3 and 10−4 
MRD grade 4 MRD4 Nonclonal plasma cells or clonotypes between 10−4 and 10−5 
MRD grade 5 MRD5 Nonclonal plasma cells or clonotypes between 10−5 and 10−6 
MRD grade 6 MRD6 Nonclonal plasma cells or clonotypes <10−6 
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