Table 2.

Details of fracture events during follow-up

VariablePatients with a fracture (N = 81)
Was the site of fracture involved at baseline?, n (%)  
 Initial DLBCL bone involvement but not at fracture site 21 (25.9) 
 Initial DLBCL bone involvement at subsequent fracture site 14 (17.3) 
 No initial DLBCL bone involvement 46 (56.8) 
Multiple sites, n (%)  
 1 63 (77.8) 
 2 14 (17.3) 
 3 3 (3.7) 
 4 1 (1.2) 
Thoracic vertebrae, n (%)  
 No 48 (59.3) 
 Yes 33 (40.7) 
Lumbar vertebrae, n (%)  
 No 55 (67.9) 
 Yes 26 (32.1) 
Any vertebrae, n (%)  
 No 28 (34.6) 
 Yes 53 (65.4) 
Femur/acetabulum, n (%)  
 No 71 (87.7) 
 Yes 10 (12.3) 
Rib/clavicle, n (%)  
 No 74 (91.4) 
 Yes 7 (8.6) 
Forearm/wrist, n (%)  
 No 76 (93.8) 
 Yes 5 (6.2) 
Humerus, n (%)  
 No 77 (95.1) 
 Yes 4 (4.9) 
Shoulder/scapula, n (%)  
 No 78 (96.3) 
 Yes 3 (3.7) 
Sacrum/pubic rami, n (%)  
 No 78 (96.3) 
 Yes 3 (3.7) 
Ankle, n (%)  
 No 78 (96.3) 
 Yes 3 (3.7) 
What was the method of diagnosis?, n (%)  
 Symptomatic 42 (51.9) 
 Incidental 39 (48.1) 
Was A&E attendance or admission required due to fracture?, n (%)  
 No 51 (63.0) 
 Yes, A&E or other unplanned attendance 16 (19.8) 
 Yes, admission 14 (17.3) 
Was there a history or trauma associated with the fracture?, n (%)  
 No 56 (71.8) 
 Yes, fall from standing or sitting 22 (28.2) 
 Missing 
Was surgery needed?, n (%)  
 No 72 (88.9) 
 Yes 9 (11.1) 
Were bisphosphonates used?, n (%)  
 No 51 (75.0) 
 Yes 17 (25.0) 
 Unclear 13 
Was opiate analgesia used?, n (%)  
 No 35 (56.5) 
 Yes 27 (43.5) 
 Unclear 19 
VariablePatients with a fracture (N = 81)
Was the site of fracture involved at baseline?, n (%)  
 Initial DLBCL bone involvement but not at fracture site 21 (25.9) 
 Initial DLBCL bone involvement at subsequent fracture site 14 (17.3) 
 No initial DLBCL bone involvement 46 (56.8) 
Multiple sites, n (%)  
 1 63 (77.8) 
 2 14 (17.3) 
 3 3 (3.7) 
 4 1 (1.2) 
Thoracic vertebrae, n (%)  
 No 48 (59.3) 
 Yes 33 (40.7) 
Lumbar vertebrae, n (%)  
 No 55 (67.9) 
 Yes 26 (32.1) 
Any vertebrae, n (%)  
 No 28 (34.6) 
 Yes 53 (65.4) 
Femur/acetabulum, n (%)  
 No 71 (87.7) 
 Yes 10 (12.3) 
Rib/clavicle, n (%)  
 No 74 (91.4) 
 Yes 7 (8.6) 
Forearm/wrist, n (%)  
 No 76 (93.8) 
 Yes 5 (6.2) 
Humerus, n (%)  
 No 77 (95.1) 
 Yes 4 (4.9) 
Shoulder/scapula, n (%)  
 No 78 (96.3) 
 Yes 3 (3.7) 
Sacrum/pubic rami, n (%)  
 No 78 (96.3) 
 Yes 3 (3.7) 
Ankle, n (%)  
 No 78 (96.3) 
 Yes 3 (3.7) 
What was the method of diagnosis?, n (%)  
 Symptomatic 42 (51.9) 
 Incidental 39 (48.1) 
Was A&E attendance or admission required due to fracture?, n (%)  
 No 51 (63.0) 
 Yes, A&E or other unplanned attendance 16 (19.8) 
 Yes, admission 14 (17.3) 
Was there a history or trauma associated with the fracture?, n (%)  
 No 56 (71.8) 
 Yes, fall from standing or sitting 22 (28.2) 
 Missing 
Was surgery needed?, n (%)  
 No 72 (88.9) 
 Yes 9 (11.1) 
Were bisphosphonates used?, n (%)  
 No 51 (75.0) 
 Yes 17 (25.0) 
 Unclear 13 
Was opiate analgesia used?, n (%)  
 No 35 (56.5) 
 Yes 27 (43.5) 
 Unclear 19 

A&E, accident and emergency department.

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