Logistic regression
| Variable (at time of HDACi start) . | Univariate models . | Multivariate model using significant univariate variables . | ||||
|---|---|---|---|---|---|---|
| Odds ratio . | P . | Estimate std . | Error . | z value . | Pr (>|z|) . | |
| TFH phenotype | 0.322 | .003 | −1.026 | 0.393 | −2.608 | 0.009 |
| Age | 0.640 | .283 | ||||
| Stage | 0.948 | 1.000 | ||||
| Extranodal involvement | 1.223 | .595 | ||||
| ECOG | 1.585 | .358 | ||||
| LDH | 1.172 | .709 | ||||
| IPI | 0.667 | .347 | ||||
| AutoSCT consolidation in first line | 0.910 | .910 | ||||
| Response to first-line chemotherapy | 2.893 | .011 | 0.926 | 0.4297 | 2.166 | 0.030 |
| Relapse within 1 y from first-line chemotherapy | 1.486 | .335 | ||||
| Lines of therapy before HDACi | 0.079 | .079 | ||||
| Combination HDACi vs single agent | 0.949 | .000 | ||||
| Variable (at time of HDACi start) . | Univariate models . | Multivariate model using significant univariate variables . | ||||
|---|---|---|---|---|---|---|
| Odds ratio . | P . | Estimate std . | Error . | z value . | Pr (>|z|) . | |
| TFH phenotype | 0.322 | .003 | −1.026 | 0.393 | −2.608 | 0.009 |
| Age | 0.640 | .283 | ||||
| Stage | 0.948 | 1.000 | ||||
| Extranodal involvement | 1.223 | .595 | ||||
| ECOG | 1.585 | .358 | ||||
| LDH | 1.172 | .709 | ||||
| IPI | 0.667 | .347 | ||||
| AutoSCT consolidation in first line | 0.910 | .910 | ||||
| Response to first-line chemotherapy | 2.893 | .011 | 0.926 | 0.4297 | 2.166 | 0.030 |
| Relapse within 1 y from first-line chemotherapy | 1.486 | .335 | ||||
| Lines of therapy before HDACi | 0.079 | .079 | ||||
| Combination HDACi vs single agent | 0.949 | .000 | ||||
Bold indicates statistically significant P values.
AutoSCT, autologous stem cell transplantation; ECOG, Eastern Cooperative Oncology Group.