Multivariate analysis of HLA-A*24 and HLA-A*32 and AML relapse following HCT
| Variable . | N . | HR . | 95% CI . | P . |
|---|---|---|---|---|
| Non-A*32/A*24 | 451 | 1.00 | 1.00-1.00 | NA |
| A*32 + KIR3DL1pos donor | 25 | 0.931 | 0.447-1.942 | .850 |
| A*24 + KIR3DL1pos donor | 110 | 1.649 | 1.172-2.320 | .004 |
| A*24 + KIR3DL1neg donor | 18 | 1.184 | 0.467-3.001 | .722 |
| Variable . | N . | HR . | 95% CI . | P . |
|---|---|---|---|---|
| Non-A*32/A*24 | 451 | 1.00 | 1.00-1.00 | NA |
| A*32 + KIR3DL1pos donor | 25 | 0.931 | 0.447-1.942 | .850 |
| A*24 + KIR3DL1pos donor | 110 | 1.649 | 1.172-2.320 | .004 |
| A*24 + KIR3DL1neg donor | 18 | 1.184 | 0.467-3.001 | .722 |
The number of patients (N), hazard ratios (HR), confidence interval (CI) and P values are shown. KIR3DL1pos donor includes donors expressing either KIR3DL1high, KIR3DL1low, or both. KIR3DL1neg group consist of donors without surface expression of KIR3DL1 (KIR3DL1null/null, KIR3DL1null/KIR3DS1, KIR3DS1/KIR3DS1).
NA, not available.