Distribution of baseline characteristics according to quartiles of plasma levels of GDF-15
| Characteristic . | Plasma GDF-15 (pg/mL) . | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Quartile 1 (<200) . | Quartile 2 (200-264) . | Quartile 3 (264-358) . | Quartile 4 (≥358) . | |||||||||
| No. of participants | 285 | 326 | 313 | 340 | ||||||||
| Age, mean ± SD, years | 49 ± 13 | 57 ± 12 | 64 ± 11 | 69 ± 11 | ||||||||
| Male sex, n (%) | 137 (48.1) | 166 (50.9) | 144 (46.0) | 147 (43.2) | ||||||||
| High-sensitivity CRP, median (25th-75th percentile), mg/L | 0.93 (0.56-1.84) | 1.18 (0.68-2.34) | 1.49 (0.89-2.68) | 1.90 (0.90-3.44) | ||||||||
| BMI, mean ± SD, kg/m2 | 25.9 ± 3.8 | 26.4 ± 4.1 | 26.7 ± 4.3 | 26.5 ± 4.7 | ||||||||
| Smoking, n (%) | 67 (23.5) | 92 (28.2) | 104 (33.2) | 131 (38.5) | ||||||||
| Hormone therapy, n (%) | 19 (6.7) | 20 (6.1) | 14 (4.5) | 7 (2.1) | ||||||||
| Physical activity, n (%)* | 76 (26.7) | 78 (23.9) | 47 (15.0) | 38 (11.2) | ||||||||
| Cancer, n (%)† | 8 (2.8) | 12 (3.7) | 19 (6.1) | 19 (5.6) | ||||||||
| Arterial CVD, n (%)‡ | 13 (4.6) | 46 (14.1) | 54 (17.3) | 87 (25.6) | ||||||||
| Characteristic . | Plasma GDF-15 (pg/mL) . | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Quartile 1 (<200) . | Quartile 2 (200-264) . | Quartile 3 (264-358) . | Quartile 4 (≥358) . | |||||||||
| No. of participants | 285 | 326 | 313 | 340 | ||||||||
| Age, mean ± SD, years | 49 ± 13 | 57 ± 12 | 64 ± 11 | 69 ± 11 | ||||||||
| Male sex, n (%) | 137 (48.1) | 166 (50.9) | 144 (46.0) | 147 (43.2) | ||||||||
| High-sensitivity CRP, median (25th-75th percentile), mg/L | 0.93 (0.56-1.84) | 1.18 (0.68-2.34) | 1.49 (0.89-2.68) | 1.90 (0.90-3.44) | ||||||||
| BMI, mean ± SD, kg/m2 | 25.9 ± 3.8 | 26.4 ± 4.1 | 26.7 ± 4.3 | 26.5 ± 4.7 | ||||||||
| Smoking, n (%) | 67 (23.5) | 92 (28.2) | 104 (33.2) | 131 (38.5) | ||||||||
| Hormone therapy, n (%) | 19 (6.7) | 20 (6.1) | 14 (4.5) | 7 (2.1) | ||||||||
| Physical activity, n (%)* | 76 (26.7) | 78 (23.9) | 47 (15.0) | 38 (11.2) | ||||||||
| Cancer, n (%)† | 8 (2.8) | 12 (3.7) | 19 (6.1) | 19 (5.6) | ||||||||
| Arterial CVD, n (%)‡ | 13 (4.6) | 46 (14.1) | 54 (17.3) | 87 (25.6) | ||||||||