Summary of related AEs
| AE . | Number of subjects (%) (n = 37) . | Number of infusions (%) (n = 318) . |
|---|---|---|
| Tachycardia | 1 (2.7%) | 1 (0.3%) |
| Infusion site paresthesia | 1 (2.7%) | 1 (0.3%) |
| Chest discomfort* | 1 (2.7%) | 1 (0.3%) |
| Generalized pruritus | 1 (2.7%) | 1 (0.3%) |
| Hot flush | 1 (2.7%) | 1 (0.3%) |
| Dysgeusia | 1 (2.7%) | 1 (0.3%) |
| Heart rate increase* | 1 (2.7%) | 1 (0.3%) |
| Electrocardiogram T wave inversions | 1 (2.7%) | 1 (0.3%) |
| AE . | Number of subjects (%) (n = 37) . | Number of infusions (%) (n = 318) . |
|---|---|---|
| Tachycardia | 1 (2.7%) | 1 (0.3%) |
| Infusion site paresthesia | 1 (2.7%) | 1 (0.3%) |
| Chest discomfort* | 1 (2.7%) | 1 (0.3%) |
| Generalized pruritus | 1 (2.7%) | 1 (0.3%) |
| Hot flush | 1 (2.7%) | 1 (0.3%) |
| Dysgeusia | 1 (2.7%) | 1 (0.3%) |
| Heart rate increase* | 1 (2.7%) | 1 (0.3%) |
| Electrocardiogram T wave inversions | 1 (2.7%) | 1 (0.3%) |
A subject with a history of allergic responses to cryoprecipitate and a pdVWF concentrate experienced simultaneous chest discomfort and increased heart rate.