Adverse events occurring in >10% of patients, regardless of attribution
| Adverse event . | Grade 1/2 . | Grade 3+ . | Any grade . |
|---|---|---|---|
| Hematologic, n (%) | |||
| Neutropenia | 1 (4) | 4 (16) | 5 (20) |
| Anemia | 1 (4) | 4 (16) | 5 (20) |
| Thrombocytopenia | 3 (12) | 2 (8) | 5 (20) |
| Nonhematologic, n (%) | |||
| Fatigue | 7 (28) | 1 (4) | 8 (32) |
| Febrile neutropenia | 7 (28) | 7 (28) | |
| Pneumonia | 1 (4) | 6 (24) | 7 (28) |
| Diarrhea | 6 (24) | 1 (4) | 7 (28) |
| Abdominal pain | 6 (24) | 6 (24) | |
| Edema | 6 (24) | 6 (24) | |
| Constipation | 5 (20) | 5 (20) | |
| Epistaxis | 3 (12) | 1 (4) | 4 (16) |
| Vomiting | 4 (16) | 4 (16) | |
| Abdominal distension | 3 (12) | 3 (12) | |
| Dyspnea | 3 (12) | 3 (12) | |
| Dizziness | 3 (12) | 3 (12) | |
| Headache | 2 (8) | 1 (4) | 3 (12) |
| Hypertension | 2 (8) | 1 (4) | 3 (12) |
| Bone pain | 1 (4) | 2 (8) | 3 (12) |
| Myalgia | 3 (12) | 3 (12) | |
| Pain | 3 (12) | 3 (12) | |
| Adverse event . | Grade 1/2 . | Grade 3+ . | Any grade . |
|---|---|---|---|
| Hematologic, n (%) | |||
| Neutropenia | 1 (4) | 4 (16) | 5 (20) |
| Anemia | 1 (4) | 4 (16) | 5 (20) |
| Thrombocytopenia | 3 (12) | 2 (8) | 5 (20) |
| Nonhematologic, n (%) | |||
| Fatigue | 7 (28) | 1 (4) | 8 (32) |
| Febrile neutropenia | 7 (28) | 7 (28) | |
| Pneumonia | 1 (4) | 6 (24) | 7 (28) |
| Diarrhea | 6 (24) | 1 (4) | 7 (28) |
| Abdominal pain | 6 (24) | 6 (24) | |
| Edema | 6 (24) | 6 (24) | |
| Constipation | 5 (20) | 5 (20) | |
| Epistaxis | 3 (12) | 1 (4) | 4 (16) |
| Vomiting | 4 (16) | 4 (16) | |
| Abdominal distension | 3 (12) | 3 (12) | |
| Dyspnea | 3 (12) | 3 (12) | |
| Dizziness | 3 (12) | 3 (12) | |
| Headache | 2 (8) | 1 (4) | 3 (12) |
| Hypertension | 2 (8) | 1 (4) | 3 (12) |
| Bone pain | 1 (4) | 2 (8) | 3 (12) |
| Myalgia | 3 (12) | 3 (12) | |
| Pain | 3 (12) | 3 (12) | |