Patient demographics and clinical laboratory data
| . | O/B (n = 57) . | A/AB (n = 38) . | P . |
|---|---|---|---|
| Demographics | |||
| Male/female, n | 34/23 | 27/11 | .26 |
| Age, y | 66 (58-73) | 71 (65-78) | .09 |
| Days from symptom onset to ICU admission | 7 (4.5-10) | 8 (5-11) | .34 |
| Source of ICU admission, n (%) | |||
| Direct from emergency room | 22 (39) | 20 (53) | .42 |
| From non-ICU | 26 (46) | 14 (37) | |
| Direct hospital transfer | 7 (12) | 4 (11) | |
| Direct facility transfer | 2 (4) | 0 (0) | |
| Comorbidities, n (%) | |||
| Hypertension | 24 (42) | 19 (50) | .45 |
| Diabetes | 17 (30) | 14 (37) | .69 |
| Dyslipidemia | 20 (35) | 14 (37) | .86 |
| Asthma | 5 (9) | 6 (16) | .29 |
| CKD | 11 (19) | 3 (8) | .12 |
| CVD | 16 (28) | 5 (13) | .09 |
| COPD | 4 (7) | 1 (3) | .35 |
| Current or former smoker | 5 (9) | 5 (13) | .49 |
| Baseline laboratory values | |||
| White blood cells, ×109/L | 7.7 (5.75-10) | 11.1 (6.4-13.3) | .02 |
| Lymphocytes, ×109/L | 0.75 (0.6-1.0) | 0.7 (0.5-1.0) | .59 |
| Platelets, ×109/L | 221 (161-266) | 219.5 (179-271) | .66 |
| AST, U/L | 40 (27-66) | 66 (37-102) | .02 |
| ALT, U/L | 56 (30-82) | 87 (53.5-106.5) | .01 |
| Bilirubin, μmol/L | 10 (6-14) | 10 (7-16) | .56 |
| Lactate, U/L | 1.3 (1-1.65) | 1.6 (1.1-1.9) | .18 |
| Creatinine, μmol/L | 85 (67-112.5) | 105 (76-133) | .07 |
| First 3 days in ICU | |||
| Highest recorded serum creatinine, μmol/L | 98.5 (72.5-154.5) | 124.5 (92-234) | .03 |
| Highest recorded fibrin D-dimer, μg/L | 1200 (631-3280) | 2472 (1173-4000) | .05 |
| Highest recorded ferritin, μg/L | 1137 (655-2329) | 1500 (820-3297) | .35 |
| Highest recorded C-reactive protein, mg/L | 142.35 (83-182) | 180 (83-267.1) | .14 |
| . | O/B (n = 57) . | A/AB (n = 38) . | P . |
|---|---|---|---|
| Demographics | |||
| Male/female, n | 34/23 | 27/11 | .26 |
| Age, y | 66 (58-73) | 71 (65-78) | .09 |
| Days from symptom onset to ICU admission | 7 (4.5-10) | 8 (5-11) | .34 |
| Source of ICU admission, n (%) | |||
| Direct from emergency room | 22 (39) | 20 (53) | .42 |
| From non-ICU | 26 (46) | 14 (37) | |
| Direct hospital transfer | 7 (12) | 4 (11) | |
| Direct facility transfer | 2 (4) | 0 (0) | |
| Comorbidities, n (%) | |||
| Hypertension | 24 (42) | 19 (50) | .45 |
| Diabetes | 17 (30) | 14 (37) | .69 |
| Dyslipidemia | 20 (35) | 14 (37) | .86 |
| Asthma | 5 (9) | 6 (16) | .29 |
| CKD | 11 (19) | 3 (8) | .12 |
| CVD | 16 (28) | 5 (13) | .09 |
| COPD | 4 (7) | 1 (3) | .35 |
| Current or former smoker | 5 (9) | 5 (13) | .49 |
| Baseline laboratory values | |||
| White blood cells, ×109/L | 7.7 (5.75-10) | 11.1 (6.4-13.3) | .02 |
| Lymphocytes, ×109/L | 0.75 (0.6-1.0) | 0.7 (0.5-1.0) | .59 |
| Platelets, ×109/L | 221 (161-266) | 219.5 (179-271) | .66 |
| AST, U/L | 40 (27-66) | 66 (37-102) | .02 |
| ALT, U/L | 56 (30-82) | 87 (53.5-106.5) | .01 |
| Bilirubin, μmol/L | 10 (6-14) | 10 (7-16) | .56 |
| Lactate, U/L | 1.3 (1-1.65) | 1.6 (1.1-1.9) | .18 |
| Creatinine, μmol/L | 85 (67-112.5) | 105 (76-133) | .07 |
| First 3 days in ICU | |||
| Highest recorded serum creatinine, μmol/L | 98.5 (72.5-154.5) | 124.5 (92-234) | .03 |
| Highest recorded fibrin D-dimer, μg/L | 1200 (631-3280) | 2472 (1173-4000) | .05 |
| Highest recorded ferritin, μg/L | 1137 (655-2329) | 1500 (820-3297) | .35 |
| Highest recorded C-reactive protein, mg/L | 142.35 (83-182) | 180 (83-267.1) | .14 |
Unless otherwise noted, data are median (IQR).
CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease; CVD, cardiovascular disease.