CNL characterized by increased neutrophils and myeloid hyperplasia. The peripheral smear shows prominent neutrophilia (A; original magnification ×600; Wright's stain). The accompanying bone marrow aspirate illustrates myeloid hyperplasia with complete maturation (B; original magnification ×600; Wright's stain). The core biopsy is hypercellular and dominated by maturing myeloid elements (C; original magnification ×600) with no increase in CD34-positive blasts (D; original magnification ×600; hematoxylin and eosin stain).