Figure 1.
Associations between individual clinical features and somatic mutations. (A) Directions, magnitude, and strength of evidence of associations between pairs of selected morphologic features and genetic mutations are shown. Pairs shown have q values (P values corrected for multiple hypothesis testing) <0.1; larger dots represent stronger evidence. Color is used to depict the magnitude of pairwise odds ratios (OR): magenta represents cooccurring traits (positive association); green reflects mutually exclusive traits (negative association). (B-C) Estimated ORs and their confidence intervals for selected pairs of genetic mutations and dysplastic (B) or cytopenic (C) features. MgK, megakaryocyte.