Asns methylation in mouse BCP-ALL models. (A) Asns methylation in leukemic spleen samples from knockin mice with ETV6-RUNX1 (red) and TCF3-PBX1 (green) and transgenic mice with BCR-ABL1 (blue). Right panels demonstrate representative histograms. (B) Methylation status of 6 genes in mouse 6qA1, a syntenic region of human 7q21, in representative leukemic spleen samples from knockin mice of ETV6-RUNX1. (C) Correlation between Asns methylation (vertical axis) and methylation level of 6 genes (horizontal axes) in leukemic spleen samples from knockin mice of ETV6-RUNX1. Correlation coefficients and P values are shown at the top of the panels.