Most common AEs. (A) Prevalence of most common TEAEs* of any grade over time† in the total safety population. (B) Most common TEAEs* in the total safety population and by prior line of therapy. URTI, upper respiratory tract infection. *Occurring in ≥20% of patients overall in the total safety population. †Prevalences of TEAEs beyond 3 years have been excluded because of small sample size (n = 7).