Knockdown of FXIII-B in rabbits. (A) Western blots against FXIII-A. Each lane contains the plasma from an individual rabbit treated with siFXIIIB-r (green) or siLuc (lavender). (B) Quantification of FXIII-A protein from panel A using densitometry. Values represent mean ± range; n = 2. (C) Western blot against α2-antiplasmin comparing HMW species in plasma clotted for 1 hour that had been collected 14 or 21 days after rabbits were treated with siFXIIIB-r or siLuc. Non-recalcified plasma was used as a control for unactivated FXIII-A.