Treatment options in newly diagnosed NLPHL. *Patients with early-stage NLPHL except for stage IA with no clinical risk factors. ^†Four cycles of escalated BEACOPP (BEACOPPesc) in case of  interim PET after 2 cycles of chemotherapy with escalated BEACOPP (PET-2) negativity, 6 cycles of BEACOPPesc in case of PET-2 positivity. ^‡Can be considered in patients with a CR according to PET and CT imaging after lymph node resection. ^§Can be considered in patients with conditions precluding the use of anthracyclines.