Telomere length and comorbidities. (A) Distribution of HCT-CI scores according to telomere length groups. (B) Association between each HCT-CI component comorbidity and the shortest or the longest telomere length group in patients age 40 years or older. The x-axis depicts the magnitude of association (log₂ odds ratio), and the y-axis shows the negative log of the P values corrected for multiple hypothesis testing (-log₁₀P). The solid line represents the threshold of significance (0.05) for FDR-corrected P values. Each circle represents 1 comorbidity; the size of the circle reflects the number of patients with a comorbidity. (C-E) Overall survival, cumulative incidence of nonrelapse mortality, and age at transplantation, respectively, by telomere length quartiles in patients with HCT-CI score 0 who received myeloablative conditioning.