Cumulative incidence of infection and infection density following CAR19. (A) Cumulative incidence time-to-event analysis among the total cohort (N = 41) showing overall time to first infection of any type, as well as subsets for bacterial, viral, and fungal infections, over the total duration of follow-up after axi-cel infusion. Patients were censored at the time of last follow-up; disease relapse or progression and death were defined as competing events. Dotted lines represent 95% CI. (B) Infection densities are shown for any type and severity, as well as subsets for bacterial, viral, and fungal infections of any severity, occurring during 4 time periods following axi-cel infusion. The same groupings are interleaved for severe (CTCAE grade ≥3) infections alone. Calculated infection densities are shown above each bar. P values shown were obtained by calculating an IRR between the first 28 days of follow-up and the remainder of follow-up using the mid-P method and comparing using Fisher’s exact test.