Survival. Kaplan-Meier curves of (A) PFS and (B) OS for all BL patients (n = 641). Kaplan-Meier curves of (C) PFS and (D) OS based on age. Three-year PFS rates for patients ages <40 vs 40 to 59 vs ≥60 years were 73% (95% CI, 67-79) vs 61% (95% CI, 55-67) vs 56% (95% CI, 47-64), respectively, P < .001; 3-year OS rates were 79% (95% CI, 73-84) vs 65% (95% CI, 58-71) vs 63% (95% CI, 54-70), respectively, P < .001. Kaplan-Meier curves of (E) PFS and (F) OS in BL patients based on ECOG performance status (PS). Three-year PFS rates for patients with ECOG PS 0 to 1 vs 2 to 4 were 71% (95% CI, 66-75) vs 50% (95% CI, 41-58) respectively, P < .001; 3-year OS rates were 76% (95% CI, 72-80) vs 53% (95% CI, 44-61), respectively, P < .001.