OS in patients with ATL with or without structural breakpoints at 2q and 5q. (A) OS in patients with ATL with structural breakpoints at 2q. Patients with a structural breakpoint at 2q had a significantly worse outcome than those without it (P = .014). (B) OS in patients with ATL with a structural breakpoint at 5q. Patients with a structural breakpoint at 5q had a significantly worse outcome than those without it (P < .001).