Figure 3.
Transcript analysis of mRNA for SG proteins revealed no distinct differences in neutrophils of patients with GPS. Heatmaps of mRNA gene expression in granulocytes of GPS patients (A-E), controls (C1, C2) and BluePrint neutrophil reference transcriptomes (BP1-BP7). Of the 34 SG transcripts expressed, 4 were differentially expressed in GPS neutrophils (red boxes in the left panel indicate differentially expressed genes). See also the study by Sims et al.26 SG proteins according to Rorvig et al.25 DE, differentially expressed.