Genomic landscape of CD34 progenitors and leukemic cells at MRD stages. Patients with undetectable (A) (N = 4) and persistent MRD (B) (N = 6) after FLUGA (light purple) or AZA (light green). Genes are distributed in rows, and columns represent paired baseline and phenotypically normal CD34 progenitors (HPCs) in patients with undetectable MRD, or paired diagnostic and blasts in patients with persistent MRD. Venn diagram shows the percentage of mutations and CNAs in blasts or HPCs detectable only at baseline, detectable only at MRD, and detectable in both time points. P value was determined by Pearson χ² for differences between treatment arms.