Summary of the laboratory features in patients with TMA. A differential diagnosis of the causes of a TMA are included, focusing specifically on cancer or its treatment and a summary of treatments beneficial in the individual subgroups. abdo, abdomen; adenoCa, adenocarcinoma; aPL, antiphospholipid; DAT, direct antiglobulin test; dsDNA, double-stranded DNA; ENA, extractable nuclear antigen; FBC, full blood count; GVHD, graft-versus-host disease; LMWH, low-molecular-weight heparin; PCR, polymerase chain reaction; RF, rheumatoid factor; SLE, systemic lupus erythematosus; STEC, Shiga toxin-producing Escherichia coli; U&E, urea and electrolytes; Vit, vitamin.