PFS of MGUS patients with and without RDs. PFS is given in years calculated from the time of MGUS diagnosis and stratified by MGUS vs MGUS-RD. RDs were grouped as follows: (1) Ab-mediated RDs (RA, connective tissue diseases such as systematic lupus erythematosus, Sjögren syndrome, mixed connective tissue disease, systemic sclerosis/ANCA-associated vasculitis) and (2) non-Ab–mediated RDs (including PMR, LV-GCA, SpA, and gout). The number of patients at risk, the number of events (eg, 154/3), and HRs [95% CIs] are shown.