Comparison of poly-EBV-L and GZL. (A) Oncoplot of mutations within polymorphic EBV DLBCL. (B) Pairwise (Fisher’s exact test) comparison of the incidence of mutations within GZL and polymorphic EBV DLBCL. The size of the bubble is inversely correlated with the P value. Significant results (P < .05 and q < 0.1) are colored in red. Full analysis is provided in supplemental Table 4D. (C) Co-oncoplot of the most recurrent mutations within poly-EBV-L, based on the presence of thymic involvement: thymic poly-EBV-L (n = 5) and nonthymic poly-EBV-L (n = 13). Genes have been selected based on the recurrence within thymic and nonthymic poly-EBV-L (>20% in either cohort or in both). (D) Bar plot showing incidence of mutations within thymic poly-EBV-L (blue) and thymic GZL (gray). (E) Bar plot showing incidence of mutations within nonthymic poly-EBV-L (green) and nonthymic GZL (purple).