Differences and commonalities in proteomic signatures of isolated vs DVT-associated pulmonary embolism. This figure depicts proteins that were selected in multiple LASSO-regularized regression models, ordered by λ ratio in the leftmost model (isolated PE vs isolated DVT). (A) Protein expression patterns specific to isolated PE are shown, as are (B) patterns that were shared between the isolated PE and DVT-associated PE phenotypes. All regression models were adjusted for age, sex, body mass index, center, and medication intake.