![Characteristics of patients with IDH1-mutated AML. (A) Volcano plot representing the association between IDH1, IDH1R132C, and IDH1R132H variants and covariates (estimate of the point-biserial correlation [continuous variables] or Φ [dichotomous variables] on the x-axis) and the significance of the difference. The P value was calculated using the Mann-Whitney U test (for continuous variables) or Fisher’s exact (dichotomous) test, expressed on an inverted logarithmic scale on the y-axis). The size of the circle corresponds to the frequency of the variable in the cohort. Only covariates with q < 0.05 are highlighted. (B) OS censored at HSCT according to the type of IDH1 variant. (C) OS censored at HSCT according to the mutational status of NPM1.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/137/20/10.1182_blood.2020010165/1/bloodbld2020010165f2.png?Expires=1742844167&Signature=zScpMSDxG5JFiOG0mBdbq42PI5-CRQNMVcXDWbzz5SiYzPTpJHEmZJNazJcSO5UwyleBJ5BATx1f2-fgceCbfr~8g38mj-DH6grJ3215BrF~sp6OFEFuJHmjP~k6A9oOHdPorN4fQwQ4MmgtTeN7rTCieY1vjVGZbXrXQCo4Zfho6eJVQC8NR0da6VAajZuFujv-Lgv9alsVbql-BJwk6XZNec-UIqgOOUJe4Kq~W9npFn7XWNj07OxjUxFEnNiVCfatYItgKhHyfV~pEhB~Iwi4F5Cbw0HllLdoL5iP9rM9YQuA45Pryse-gQ~RqUBg9Mx3UMGHqUjKnYasadGhvw__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Characteristics of patients with IDH1-mutated AML. (A) Volcano plot representing the association between IDH1, IDH1R132C, and IDH1R132H variants and covariates (estimate of the point-biserial correlation [continuous variables] or Φ [dichotomous variables] on the x-axis) and the significance of the difference. The P value was calculated using the Mann-Whitney U test (for continuous variables) or Fisher’s exact (dichotomous) test, expressed on an inverted logarithmic scale on the y-axis). The size of the circle corresponds to the frequency of the variable in the cohort. Only covariates with q < 0.05 are highlighted. (B) OS censored at HSCT according to the type of IDH1 variant. (C) OS censored at HSCT according to the mutational status of NPM1.