NGS of plasma cfDNA and tumor gDNA in NKTCL of the training cohort. (A) Overview of baseline mutational profiles in the entire training cohort. (B) Case-level genetic alterations of tumor gDNA and plasma cfDNA in 16 patients with paired plasma/tumor samples. Match indicates variants identified in both tumor gDNA and plasma cfDNA. Formalin-fixed paraffin-embedded (FFP) specific indicates variants identified in tumor gDNA only. Plasma (PLA) specific indicates variants identified in plasma cfDNA only. CN, copy number.