Neurologic monitoring of case 1 during grade 3-4 ICANS. (A) Continuous vEEG showed generalized 2.5 Hz δ activity with a triphasic morphology. (B) Electrographic resolution of seizures on vEEG after empiric lorazepam. (C) Continued electrographic resolution of seizures after treatment with levetiracetam, lacosamide, and rimiducid. (D) Optic nerve sheath diameter tracings before and after rimiducid were within the normal range and not indicative of elevated intracranial pressure. A cutoff of >5.5 mm was used to indicate possibly elevated intracranial pressure.