Percentage change in the sum of the product of diameters and maximum percent change in the standard uptake value in efficacy evaluable patients (n = 90). Sum of the product of diameters (SPD; A) and maximum standard uptake value (SUV; B) percentage changes are calculated from the baseline SPD/SUV to the minimum postbaseline SPD/SUV measured prior to initiation of subsequent chemotherapy or radiotherapy (including conditioning regimen for ASCT). Best response was determined per Lugano 2014,^17,18  with PET scanning required until assessment of CMR or PD. Patients without postbaseline tumor assessment are excluded.