Figure 5.
Patients given standard-of-care transplants and ATG differ from patients given TLI + ATG conditioning and HCT. Blood samples were obtained before and 1.5 to 4 months after transplantation from a control group of standard-of-care KTx recipients given ATG (n = 5-6). (A) Changes in the mean (± standard error of the mean [SEM]) percentage of T cells among PBMCs. (B) Changes in the absolute numbers (Abs #) of T cells. (C) Changes in the mean (± SEM) percentage of total phenotypic MDSCs among PBMCs. (D) Changes in the absolute numbers (Abs #). (E) Changes in the percentage of CD15+ pmn MDSCS. (F) Changes in the absolute numbers (Abs #) of CD15+ pmn MDSCs. (G) Changes in the percentage of Lox-1+ pmn MDSCs. (H) Changes in the absolute numbers (Abs #) of Lox-1+ pmn MDSCs. P values were determined by the Mann-Whitney U test of independent means. Means were calculated from blood samples such that n = 5 or 6 patients for each time point were used. ns, not significant.

Patients given standard-of-care transplants and ATG differ from patients given TLI + ATG conditioning and HCT. Blood samples were obtained before and 1.5 to 4 months after transplantation from a control group of standard-of-care KTx recipients given ATG (n = 5-6). (A) Changes in the mean (± standard error of the mean [SEM]) percentage of T cells among PBMCs. (B) Changes in the absolute numbers (Abs #) of T cells. (C) Changes in the mean (± SEM) percentage of total phenotypic MDSCs among PBMCs. (D) Changes in the absolute numbers (Abs #). (E) Changes in the percentage of CD15+ pmn MDSCS. (F) Changes in the absolute numbers (Abs #) of CD15+ pmn MDSCs. (G) Changes in the percentage of Lox-1+ pmn MDSCs. (H) Changes in the absolute numbers (Abs #) of Lox-1+ pmn MDSCs. P values were determined by the Mann-Whitney U test of independent means. Means were calculated from blood samples such that n = 5 or 6 patients for each time point were used. ns, not significant.

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