WBC count vs time (in months) with major events labeled. The numerals 1 to 4 indicate corresponding time points of correlative analyses. Allo HSCT, allogeneic hematopoietic stem cell transplantation; CHR, complete hematologic remission; hyperCVAD, cytarabine, vincristine, doxorubicin, dexamethasone; MEC, mitoxantrone, etoposide, cytarabine.