Pharmacokinetic variables of Mim8 in the cynomolgus monkey. Plasma exposure levels (mean ± standard deviation, n = 4 and 6) of Mim8 and endogenous FIX and FX after IV (left panel) or single-dose (1 mg/kg) SC (right panel) administration, respectively, are shown. For the IV route, 4 dose levels were explored. These were divided between 2 arms and 2 dosing occasions as indicated. Times of administration are marked by dashed vertical lines.