mRNA levels of CXCR5, BAFF-R, BCMA, and TACI of B cells. (A, B) The mRNA level of B-cell CXCR5 from patients with ITP was also higher than that from HCs, both in BM (0.070 ± 0.021 vs 0.016 ± 0.007; P = .034) and PB (median [range], 0.071 [0.015 to 0.338] vs 0.035 [0.017-0.089]; P = .017). (C, D) Increased mRNA levels of BAFF-R in BM (0.066 ± 0.020 vs 0.011 ± 0.003; P = .024) and PB (median [range], 0.090 [0.010-0.443] vs 0.030 [0.012-0.115]; P = .023) B cells from patients with ITP was found compared with HCs. (E, F) Elevated mRNA levels of BCMA were observed in BM B cells of patients with ITP compared with HCs (0.049 ± 0.011 vs 0.012 ± 0.002; P = .011), whereas no statistical difference was found in PB B cells between patients with ITP and HCs. (G, H) TACI mRNA levels of BM B cells in patients with ITP were also higher than those in HCs (0.064 ± 0.018 vs 0.016 ± 0.004; P = .034); no statistical difference was reached in PB B cells between patients with ITP and HCs. *P < .05; **P < .01; ***P < .001.