Patterns of variability in a second cohort of donors. (A) Scree plot demonstrating how much variability is captured by each PC. The first 3 PCs (PC1-3) capture 76% of the variability. (B) Biplot of PC1 and PC2. Measures of sensitivity (red) are distinct from capacity (blue). (C) Biplot of PC1 and PC3. (D) Donors from cohort 1 (prefix D) and cohort 2 (prefix C) shown on the plane of the first 2 PCs. Color code as in Figure 5. (E) Cohort 1 donors at original assessment and at recall (denoted by suffix B) displayed on the plane of the first 2 PCs.